EIO - ISmart Codon Permutator Technology/ Industrial enzymes
Metgen Ltd has applied laccase enzyme for cleantech applications by developing enzymes for biomass treatment. The enzymes are used for energy savings in the pulp and paper industry and biomass treatment for extracting chemical from cellulosic biomass.
MetGen Ltd was established in 2008 and its head office is in Turku, whereas the company operates in Europe and the USA. In addition to the industiral enzymes, the company is also an active operator in the development and production of biopharmaceuticals. MetGen's biocatalytical procesess make the production processes faster, cleaner and less expensive.
Laccase enzymes occur naturally in fungi and they are able to decompose various organic compounds including lignin (chemical binding the cells of wood plants). The enzymes belong to the multinuclear copper-containing oxidases and their uses span from the textile to pulp and paper industry and from wood applications to bioremediation.
Practically, MetGen's Smart Codon Permutator technology carefully selects the gene sites to be mutated and synthesis representative oligo libraries. The proprietary technology offers a remarkable advantage over existing technologies in terms of selectivity, productivity and the final cost of the desired industrial enzymes. The enzymes are used for energy savings in the pulp and paper industry and biomass treatment for extracting chemical from cellulosic biomass.
Barriers and Drivers
Drivers: The enzymes improve the fiber strength and de-ink used paper mass and produces improved yield of bioethanol from cellulosic waste for the biofuel industry. MetGen also designs enzymes to fit customer conditions and their enzymes are effectively priced and easy to produce. The company has already managed to network with industrial customers and create a market for their solutions.
Barriers: The method does not work in high temperatures (over 80 celsius) or pHs. In addition, MetGen is not a one-stop solution provider and large-scale production would require outsourcing.
Manufacturing costs can be reduced as much as 70%, and thus can solve the critical issue of energy efficiency issues related to industrial processes using laccases. Furthermore, MetGen's industrial enzymes can be utilised in several different industries.
Remarkable savings in energy use in pulp and paper industry. However, the methods also generate cleaner production process. In addition, the oxidoreductases are environmentally friendly and the only byproducts of the process is water.